top of page
landscape image with a white background. starting in  the top left corner and stretching t

Revolutionary Drug Discovery, Tailored to Your Pipeline

Screening billions of molecules has never been easier.

​​​Providing custom discovery services that are efficacious and cost-efficient to biotech companies, academic labs, pharma, and startups.

+ VirtualFlow

+ Enamine REAL Space

+ AI/ML

Founded in 2020

5+ Years of Molecule Discovery & Optimization

Based in Boston

Spun out of a lab at Harvard Medical School

We harness the power of VirtualFlow (Nature 2020) ​to provide virtual screens that traverse vast chemical spaces of over 60 billion molecules.

 

We use advanced techniques in AI/ML and computational chemistry to support the discovery and optimization process. 

Services

Target Analysis

Molecular Dynamics (MD) Simulations to study target dynamics 

Clustering & Markov State Modeling (MSM)

Hit Identification

Ultra-large virtual screens of the REAL Space & Zinc15
 

Small-scale docking to verify proof-of-concept

Virtual Screens on custom libraries of any size (from 1000s to millions)

Lead Optimization

Custom analog library creation using classical methods or generative models

High-accuracy virtual screen of this analog library

Screen protein-protein interactions, nucleic acids, soluble/membrane proteins, and other targets traditionally considered "undruggable" 

What type of targets can you screen?

Who has Virtual Discovery worked with?

How long does a typical project take?

What makes Virtual Discovery different from other drug discovery platforms?

Do you use VirtualFlow 2.0?

How do I get started with a service?

CONTACT
Crystal Spheres
Let's Connect

Thanks for submitting!

bottom of page